AI overview
AI generated. Not medical advice.What it's for
General wellness support; Antioxidant support; Immune support; Seasonal support
Who it may fit
Adults with busy schedules seeking short-term seasonal wellness support or those with low fruit and mushroom intake looking for added daily defense nutrients.
Key actives per serving
- Grapefruit Seed Extract: 250 mg
- Vitamin C (as calcium ascorbate): 125 mg (207% DV)
- Zinc (as gluconate): 5 mg (33% DV)
- Reishi Mushroom Extract (4:1): 100 mg
- Echinacea angustifolia Extract (4:1): 50 mg
How to take
Adults take 1 tablet daily for up to two weeks, with or without meals; taking with food may improve tolerance for botanicals.
Diet / Allergen fit
Gluten Free; Made without soy, milk, egg, yeast, wheat, sweeteners, preservatives, and GMOs.
Ingredients explained
Grapefruit Seed Extract
Provides bioactive polyphenols that may influence microbial balance and oxidative stress pathways.
Caution: May interact with certain medications and can cause stomach upset in some people; take with food if sensitive and check for drug interactions.
Vitamin C (as calcium ascorbate)
Functions as an antioxidant and cofactor for enzymes involved in collagen formation and cellular protection.
Caution: High doses may cause digestive discomfort; buffered forms like calcium ascorbate are often gentler on the stomach.
Zinc (as gluconate)
Acts as a cofactor for numerous enzymes involved in cellular signaling and antioxidant defenses.
Caution: Excess zinc over time may affect copper balance; avoid taking multiple zinc supplements concurrently.
Reishi Mushroom Extract (4:1)
Contains polysaccharides and triterpenes that are studied for modulating immune cell activity and antioxidant capacity.
Caution: May cause digestive upset in sensitive individuals; discontinue if rash or stomach discomfort occurs.
Echinacea angustifolia Extract (4:1)
Provides alkylamides and phenolics that are studied for influencing innate immune signaling.
Caution: People with plant allergies in the Asteraceae family may be more likely to experience sensitivity.
How they work together
Vitamin C and zinc provide foundational antioxidant and enzymatic support, while mushroom extracts like reishi offer polysaccharides that influence immune cell activity. Grapefruit seed extract and echinacea add botanical compounds that act on microbial balance and innate immune pathways. Together, these components address both cellular defense and general wellness functions.
Safety and tips
Label Warning: Do not exceed suggested use. Not for use during pregnancy unless a licensed healthcare professional is consulted. Not recommended for children under 12 years of age.
Who should be cautious: People taking statins or calcium channel blockers should be cautious with grapefruit seed extract. Those with gallbladder concerns or on blood-thinning medications may be sensitive to ginger. Individuals with ragweed or related plant sensitivities may react to echinacea or yarrow. People with autoimmune conditions should use echinacea cautiously. People with diabetes or on blood-sugar-lowering medications should be cautious with Oregon grape root. Those on multiple medications should consult a healthcare provider before use due to potential interactions with grapefruit extract.
What customers say
Noticeable wellness support
Many users feel better overall and say they get sick less often after adding it to their routine.
Helps at early signs of discomfort
Customers say it seems to help when they notice throat or sinus discomfort starting, and they like the quick response.
Effects vary by individual
Some feedback notes mixed results, and experiences may not be the same for everyone.
Product rankings:
iHerb Quality Promise
This product is guaranteed authentic and backed by our easy returns & refunds policy. Details
Grapefruit Seed Extract may support gut health, and probiotics can enhance beneficial gut bacteria, promoting a balanced digestive system.
AI generated. Not medical advice.
Overview
- Where Science Works Naturally®
- 250 mg Grapefruit Seed Extract
- With Echinacea, Astragalus, Vitamin C, Mushroom Extracts, Oregon Grape Root & Ginger Root
- Dietary Supplement
- Naturally Fresh - Nitro Pak® - Bacteria Free Environment
- Not Tested On Animals
- Gluten Free
NutriBiotic DefensePlus® Tablets are a unique formulation combining grapefruit seed extract, vitamin C, echinacea extract, astragalus root, ginger root extract, Oregon grape root, yarrow extract, zinc, and the mushroom extracts of reishi, maitake, and shiitake and are used by healthcare professionals worldwide.
Specifications
- First available: 05/2007
-
Shipping weight:
0.18 kg
- Product code: NBC-01015
- UPC: 728177010157
- Package quantity: 90 count
- Dimensions: 10.9 x 6.1 x 6.1 cm , 0.18 kg
Suggested use
At first signs of imbalance or depressed resistance, take one tablet daily with or without meals for two weeks. Not recommended for children under 12 years of age.
Other ingredients
Microcrystalline cellulose (binder), dicalcium phosphate, stearic acid, dextrose, silica dioxide, magnesium stearate (vegetable lubricant), and natural food glaze coating.
Made without soy, milk, egg, yeast, wheat, sweeteners, preservatives, and GMOs.
Warnings
Keep out of reach of children. Do not exceed suggested use or use during pregnancy without consulting a licensed healthcare professional.
Disclaimer
While iHerb strives to ensure the accuracy of its product images and information, some manufacturing changes to packaging and/or ingredients may be pending update on our site. Although items may occasionally ship with alternate packaging, freshness is always guaranteed. We recommend that you read labels, warnings and directions of all products before use and not rely solely on the information provided by iHerb.
| Supplement facts | ||
| Serving Size: 1 Tablet | ||
| Servings Per Container: 90 | ||
| Amount Per Serving | % DV | |
| Vitamin C (as Meta-C® calcium ascorbate) | 125 mg | 207% |
| Zinc (gluconate) | 5 mg | 33% |
| Grapefruit Seed Extract | 250 mg | * |
| Astragalus Root | 100 mg | * |
| Reishi Mushroom Extract (4:1) | 100 mg | * |
| Echinacea Angustifolia Extract (4:1) | 50 mg | * |
| Ginger Root Extract (6:1) | 50 mg | * |
| Maitake Mushroom Extract (4:1) | 50 mg | * |
| Oregon Grape Root | 50 mg | * |
| Shiitake Mushroom Extract (4:1) | 50 mg | * |
| Yarrow Extract (6:1) | 50 mg | * |
| * Daily value (DV) not established. | ||